Research projects

Alfonso Calvo Team

Active Spain

Lung cancer

Can we stop cancers hiding from immunotherapy?

This project hopes to find a way for immunotherapies to work better, for more cancer patients. Using cutting-edge technologies they will test out a potential new way to treat cancer and explore how to advance it towards the clinic. 

Researcher: Dr Alfonso Calvo

Can we stop cancers hiding from immunotherapy?

Active USA

Prostate cancer

Can we use ‘minibodies’ to detect and treat cancer?

This project hopes to develop a new way to identify and target prostate and breast cancer cells in the body using tiny molecular ‘flags’, called minibodies. 

Researcher: Dr Tanya Stoyanova

Mini but mighty: Using ‘minibodies’ to detect and treat prostate cancer
Headshot of Worldwide Cancer Research scientist Dr Claire Fletcher

Active United Kingdom

Prostate cancer

Can we damage prostate cancer cells with a tiny DNA-like material?

This project aims to find vital new treatments for advanced prostate cancer that stops responding to other treatments or comes back after treatment.

Researcher: Dr Claire Fletcher

Developing a brand-new treatment for advanced prostate cancer

Active Italy

General cancer research

Is it possible to predict which tumours can spread to other parts of the body? 

Most cancer deaths are caused by cancer spreading to different organs so this project hopes to find a new way to detect and even stop cancer spreading.

Researcher: Professor Stefano Santaguida

The role of the self-eating receptor p62 in stopping cancer spreading

Active Cyprus

Brain cancer

Can fruit flies help us understand how brain cancer develops?

Using fruit flies to discover how glioblastoma ‘hijacks’ blood vessels and takes nutrients from healthy cells, so possible new treatment targets can be found.

Researcher: Professor Chrysoula Pitsouli

Using fruit flies to understand how brain cancer can hijack our blood vessels

Active Italy

Liver cancer

Why do some people with liver disease go on to develop liver cancer?

Researchers are exploring how liver cells respond to stress causes by liver disease,  how this links to cancer development and if it can be stopped. 

Researcher: Professor Giannino Del Sal

Uncovering the connection between liver disease and liver cancer

Active Italy

General cancer research

Can we stop cancer spreading by mimicking the beating of the heart?

Discovering why cancer rarely develops in the heart will hopefully lead to an exciting new wearable device to stop cancer spreading in other organs. 

Researcher: Dr Serena Zacchigna

Treating cancer with a heart beat

Active Italy

Leukaemia

What causes JMML – a rare childhood blood cancer?

JMML (Juvenile myelomonocytic leukaemia) affects very young children and is hard to treat, so this project is looking at what causes it to try to find new cures.

Researcher: Dr Emanuele Azzoni

Pursuing new clues about the cause of a rare childhood blood cancer