Research projects

Active Spain

Breast cancer

How does a faulty BRCA2 gene cause breast cancer to develop?

The team hope that by understanding how different mutations contribute to breast cancer, they can reveal new ways to prevent, diagnose and treat it.  

Researcher: Dr Aura Carreira

Uncovering how a faulty BRCA2 gene causes breast cancer to develop

Active Italy

General cancer research

Can we stop cancers hiding from our immune systems?

This project hopes to discover clues about new ways to provide personalised immunotherapy treatments for patients with many different cancer types.  

Researcher: Professor Stefano Biffo

Developing a new model of the immune response to tumours

Active Italy

Bowel cancer

Can the gut microbiome help make immunotherapies more effective?

By studying the microbes living in the guts bowel cancer patients researchers hope to reveal new ways to make immunotherapies more effective.

Researcher: Dr Luigi Nezi

Targeting the gut microbiome to make immunotherapies more effective

Active Italy

General cancer research

Can we visualise the earliest stages of cancer developing?

Researchers hope to discover whole new ways to prevent and treat cancer in the future by using a powerful new technique to study how cancer grows.

Researcher: Dr Davide Mazza

Visualising the earliest stages of cancer

Active United Kingdom

Melanoma

How does melanoma adapt to spread and seed new tumours?

Cancers is easier to treat when caught early so this project hopes to reveal new treatments that could stop melanoma spreading, helping survival rates.

Researcher: Professor Victoria Sanz-Moreno

Understanding how melanoma adapts to spread and seed new tumours

Active Italy

General cancer research

How does a genetic mutation make cells unstable and cancerous?

Mutations to a certain gene lead to several types of cancer, so this project hopes to find new future cures by better understanding the role of this mutation.

Researcher: Dr Diego Pasini

Tipping the scales: How a genetic mutation makes cells unstable

Active Greece

Brain cancer

Can fruit flies help us understand how brain tumours spread?

Unfortunately most brain tumours return despite treatment so researchers are hope to find clues towards future cures which could improve outcomes for patients. 

Researcher: Professor Christos Delidakis

Model brains: Using fruit flies to understand how brain tumours spread

Active United Kingdom

Breast cancer

Can blocking ‘bio-parcels’ stop breast cancer spreading?

Researchers hope to reveal whether groundbreaking  new drugs could stop breast cancer spreading which would make this common cancer much easier to treat.

Researcher: Professor Edward Tate

Blocking bio-parcels to stop breast cancer spreading

Active Greece

Bowel cancer

How do bowel cancers hijack healthy cells to help them grow?

This project hopes to reveal vital new ways to stop bowel cancer developing by better understanding how cancer cells and healthy cells interact. 

Researcher: Dr Vasiliki Koliaraki

Understanding how colorectal tumours hijack healthy cells