Like molecular clockwork – how biological timers control the immune system
Cancer types:
Lymphoma
Project period:
–
Research institute:
The Walter and Eliza Hall Institute of Medical Research
Award amount:
£217,541
Location:
Australia
Professor Philip Hodgkin and his team aim to get a better grip on how the immune system works when activated and how this knowledge can help to better understand the development of certain blood cancers.
Meet the scientist
Philip Hodgkin is a professor and division head at the Walter and Eliza Hall Institute of Medical Research in Victoria, Australia. His lab use computational models to understand how cells communicate and work together as part of the immune system.
The science
Professor Philip Hodgkin, based in Australia, is using funding from Worldwide Cancer Research to work out the molecular "clockwork" behind biological timers that control how the immune system responds once it is activated. His team are particularly interested in looking at genes that keep these timers ticking that are also involved in lymphoma. They hope that their approach will reveal more about how the normal immune response works so that they can identify what is going wrong when lymphoma develops.