Research projects

Active United Kingdom

Sarcoma

What causes synovial sarcoma, a rare and aggressive cancer?

Many synovial sarcoma tumour patients don’t respond well to treatments so this project wants to find new cures by better understanding what causes it.

Researcher: Dr Gerard Brien

Understanding the cause of synovial sarcoma to improve survival

Complete Italy

Breast cancer

Can we design better treatments for triple-negative breast cancer?

Researchers are developing a highly innovative way to deliver treatments directly to tumours to improve survival rates of aggressive breast cancer.

Researcher: Dr Greta Varchi

Developing a delivery system to improve treatment for aggressive breast cancer

Active Australia

Melanoma

Can our blood vessels help immunotherapy work better for melanoma?

Immunotherapy has helped improve melanoma survival rates but it doesn’t work for everyone so this project hopes to find ways for more patients to benefit.

Researcher: Professor Ruth Ganss

Improving the effect of immunotherapies for melanoma skin cancer

Complete United Kingdom

General cancer research

What cancers will respond best to treatments that damage their DNA?

Researchers hope to discover which cancers are likely to respond best to different treatment options, to improve patient outcomes in the future.

Researcher: Dr Peter Sarkies

Epigenetics – exploring one of cancer’s weak spots

Active Spain

Prostate cancer

How can healthy cells contribute to aggressive prostate cancer?

Prostate cancer can be very hard to treat when found at a later stage so this project hopes to pave the way towards future cures for these more aggressive cancers.

Researcher: Dr Mariona Graupera

How can healthy cells contribute to aggressive prostate cancer?

Active United Kingdom

General cancer research

Can we predict which patients will respond to immunotherapy?

This project hopes to open up exciting possibilities for personalised cancer treatment by finding how to predict which patients will respond best to treatment.

Researcher: Professor Tim Elliott

Finding ways to predict which patients will respond to immunotherapy

Active United Kingdom

Lymphoma

Can we find a way to switch anti-cancer genes back on?

This project will explore a cancer mutation which could be key to finding  new way stop cancer progressing, opening the door to future new treatments.

Researcher: Professor Richard Jenner

A new way to switch anti-cancer genes back on

Complete Ireland

Breast cancer

How can we start new cures for invasive lobular breast cancer?

This project hopes to pave the way towards more treatment options for patients with a type of breast cancer which often becomes resistant to current therapies.

Researcher: Professor Darran O'Connor

Finding a new treatment for invasive lobular breast cancer

Complete Italy

Kidney cancer

How can we stop an inherited syndrome causing kidney cancer?

This project hopes to kickstart a new way to prevent kidney cancer developing by better understanding the process that puts some families at a higher risk.

Researcher: Dr Chiara Di Malta

Trying to stop the development of kidney cancer in Birt-Hogg-Dubé syndrome