Research projects

Active United Kingdom

General cancer research

Can we stop cancer becoming resistant to chemotherapy?

Chemotherapy can sometimes stop working, so this project is hoping to better understand why and find ways to give more, better options to cancer patients.

Researcher: Dr Andrew Beekman

Stopping cancer becoming resistant to chemotherapy

Active Spain

Breast cancer

Can we find better breast cancer treatments with fewer side effects?

Since breast cancer is one of the most common cancers, researchers are hoping to find vital treatments by targeting a type of cell involved in cancer growth. 

Researcher: Dr Joaquín Arribas

Seeking kinder treatments for breast cancer

Active Australia

Melanoma

Could melanoma be treated with a vaccine?

Melanoma is an aggressive type of skin cancer which can be hard to treat so this project is looking to kick-start a game-changing vaccine which could be a new type of cure. 

Researcher: Dr Joanna Groom

Precision vaccines and the potential for better immunotherapies

Active United Kingdom

Oesophageal cancer

How does the genetic disease tylosis cause oesophageal cancer?

Researchers hope to reveal ways to diagnose oesophageal cancer sooner and help treatments work better by better understanding the earliest stages of the disease.

Researcher: Dr Diana Blaydon

Revealing the earliest signs of oesophageal cancer

Active United Kingdom

Leukaemia

How does infant leukaemia develop and how can we stop it?

Infant leukaemia is very difficult to treat so researchers are hoping to better understand its unique biology to reveal vital better and kinder treatments.

Researcher: Professor Katrin Ottersbach

Identifying new treatments for infant leukaemia

Active Australia

Leukaemia

Can we help immunotherapies treat leukaemia better?

This project hopes to reveal new, better, immunotherapy treatments for leukaemia by boosting a different cell in our immune system from other treatments. 

Researcher: Professor Jamie Rossjohn

Revealing the role of natural killer cells in cancer immunity

Active USA

Multiple cancers

What makes it easier for some cancers to spread to other organs?

Exploring how ‘messages’ sent from cancer cells to other parts of the body might help cancers to spread and whether new cures could stop this process.

Researcher: Dr Inbal Wortzel

A new way to predict and treat the spread of cancer

Active United Kingdom

Neuroblastoma

Can we target neuroblastoma cells without harming healthy cells?

Lots of cancer drugs cause nasty side effects by affecting healthy cells, so this project is looking for ways to turn on drugs only when they are in the tumour. 

Researcher: Professor Robert Falconer

Target acquired: Making ‘prodrugs’ for neuroblastoma that leave healthy cells unharmed

Active Belgium

Lung cancer

Can we re-wire our cells to help our immune system attack cancer?

Immunotherapy doesn’t always work but researchers hope to find ways to re-wire some of our cells so that these treatments can help more patients in the future.

Researcher: Professor Peter Carmeliet

Rewiring blood cells that block the immune response with AI